I started a set of new drugs on January 25th. There are usually no nausea effects and I'm not required to take Neupogen or my anti-nausea drugs from cycle 5 on. I'm taking new drugs for cycles 5 thru 8 Side effects range from joint and nerve pain, insomnia, gastrointestinal issues, and of course my friend, fatigue. Days 2 thru 5 became progressvely more painful; I could feel my muscles and joints seizing up - they felt like they were turning to cement. And then the nerve pain began and became progessively worse for 4 days. The balls of my feet were very painful and I almost felt weak. I walked like someone 100 years old.
Generally speaking I would say that I have a high tolerance for pain, however this was worse than anything I've ever experienced. The nerve pain caused throbbing pain almost like what you'd have with a very bad toothache or a migraine. I took Tylenol extra strength, T3's and 1200 mg of Ibupropen several times a day. Very little relief from any of them! It was brutal! I spent most of the time on the chesterfield trying to get comfortable. I finally retreated to my bed for a day and a half. Not much fun. I finally turned a corner late on day 4 and felt much better by bedtime on day 5. The remaining 2 weeks of the cycle were fine, other than fatigue which comes and goes throughout the days.
This cycle began on Feb 16th and was pretty much a repeat of cycle 5. I tried to get ahead of the pain by taking Tylenol, T3's and/or Ibruprophen on day 2 before the pain started however that didn't seem to have much effect. Again by the end of those few days I had retreated to my bed where I could get more comfortable. The pain lasted a day longer this time and I didn't seem to bounce back quite as quickly in this round. However once recovered from the side-effects, I felt good and was able to
get out a do a few things.